Find out how ORENCIA
works differently

RA can be a vicious cycle

When you have rheumatoid arthritis, there’s a lot going on inside your body. Essentially, your immune system is attacking itself. This cycle is what leads to permanent damage in your joints.

Gif of how ORENCIA works in RA. Further description in transcript below. Gif of how ORENCIA works in RA. Further description in transcript below.
Gif of how ORENCIA works in RA. Further description in transcript below.

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Your immune system thinks your joints are under attack

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So, it responds by sending signals to launch its own attack

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This attack leads to the symptoms in your joints

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Without treatment this cycle continues

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But ORENCIA disrupts a key source of signals to help break this cycle.


ORENCIA helps break the cycle

ORENCIA is the first and only treatment of its kind for RA. It works differently by preventing a key source from sending harmful signals.

A deeper dive into the science

The key source of signals that ORENCIA disrupts is called a T cell.

When your immune system thinks your joints are under attack, it activates your T cells. These activated T cells send the signals that eventually lead to the symptoms in your joints.

ORENCIA helps stop the T cell from being activated, which disrupts harmful signals from being sent to your joints.

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